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Speed up your Clustal alignments by combining Clustal with the power of Sequencher's Assemble by Name functionality for aligning multiple sequences from different sources.
Sequencher DNA序列分析软件是科学家们*的工具。持续发展和改进**过25年，Sequencher提供了**的功能特征，成千上万的出版物都有相关的应用介绍。新手用户可以以少的时间投资产生结果，而有经验的用户会惊叹于功能的深度和控制。Sequencher自带各种专有算法，可以为Sanger, Next-Gen Sequencing (NGS)和RNA-Seq序列数据生成结果。
Sequencher通用装配工具应用如下
基因变异与参考序列的比较
确认向量构造
组装病毒和基因组
从cDNA库中集群数万个序列
将cDNA组合成基因组序列
创建引物图
组装参考
参考序列功能强大，它是测序和序列分析等的核心功能。无论您是从事法、系统研究、遗传学或人口研究，您都可能使用到参考序列功能。在GenBank格式中导入一个序列，将其特性表应用到序列中，并将其标记为一个引用序列。组装到参考序列意味着您可以将您的阅读和原型参考序列进行比较。如果您使用来自不同来源的多个示例，您甚至还可以按名称装配来自动化您的工作。
您甚至可以使用参考序列来去除您感兴趣区域之外的序列或者填补序列覆盖的空白。
MUSCLE is said to have four major steps in its alignment process. The first step constructs a distance matrix between pairs of sequences using k-mer clustering, this is then converted into a tree. The second step uses this tree to guide a progressive alignment. In the final two steps, the MUSCLE algorithm tries a number of different methods to see if it is possible to improve the tree and hence the multiple alignment.
We also added the charts you would expect to see, such as the Volcano plot, so you can view the results without resorting to the command line. Because we know you have your own favourite aligners we donÔÇÖt insist you use ours. As long as your aligner creates SAM or BAM as its output you are ready to explore your data with one of the most widely regarded RNA-Seq tools available.
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