使用期限*
许可形式单机
原产地美国
介质下载
适用平台windows,mac
科学软件网提供的软件覆盖各个学科，软件数量达1000余款，满足各高校和企事业单位的科研需求。此外，科学软件网还提供软件培训和研讨会服务，目前视频课程达68门，涵盖34款软件。
Sequencher DNA序列分析软件是科学家们*的工具。持续发展和改进**过25年，Sequencher提供了**的功能特征，成千上万的出版物都有相关的应用介绍。新手用户可以以少的时间投资产生结果，而有经验的用户会惊叹于功能的深度和控制。Sequencher自带各种专有算法，可以为Sanger, Next-Gen Sequencing (NGS)和RNA-Seq序列数据生成结果。
Sanger序列
Sequencher使传统的序列装配变得*，同时又能让您保持对序列的控制。精简数据质量差的序列。您甚至可以创建一个整洁的标准库，让一切变得更简单。通过直观的控制，您可以为数据选择佳算法，包括汇编到参考中。如果您正在处理来自不同来源的多个示例，可以通过名称来对它们进行自动装配。使用工具编辑数据从来没有如此简单过，帮助您定位和处理模棱两可的问题，还可以检查杂合子并移动您的数据。使用信任值帮助修整数据、质量检查和SNP检测，以提高数据结果的质量。
序列编辑
Sequencher提供一个DNA序列编辑工具，您需要确保这个序列是正确的。您可以在一个序列中查看一次您的色谱数据或在正向和反向方向查看多个对齐的色谱图。
它可以快速、方便地滚动对齐的数据，或者可以使用Sequencher的选择工具来**区域的差异或低质量。
MUSCLE
MUSCLE[2], a multiple-sequence alignment (MSA) program, joins the Sequencher 5.1 family of plugins. It joins Clustal, making it the second MSA program in Sequencher’s DNA-Seq Tools. Boasting both speed and accuracy, it compares very favorably [3] to other multiple-sequence alignment programs.
MUSCLE is said to have four major steps in its alignment process. The first step constructs a distance matrix between pairs of sequences using k-mer clustering, this is then converted into a tree. The second step uses this tree to guide a progressive alignment. In the final two steps, the MUSCLE algorithm tries a number of different methods to see if it is possible to improve the tree and hence the multiple alignment.
Once the process is complete and MUSCLE has built the alignment, you will see the results as a contig within Sequencher. Use Sequencher’s tools to annotate your alignment or export your alignment and place it into a special phylogenetics program.
In the NGS space, trust the accuracy of your work to peer-reviewed and published algorithms and tools such as GSNAP for reference-guided alignment, Velvet for de novo assembly, Cufflinks for RNA-Seq Differential Expression and Tablet for visualization. The design and effort that goes into Sequencher makes them easy to use because once you have learned how to use one, you have learned how to use them all.
SNP Detection
Sequencher has several powerful tools to help you detect mutations and SNPs in your DNA sequences. You can use Sequencher for comparative sequence alignments among a group of sequences, or to compare 1 or more sequences to a Reference Sequence. Sequencher’s Call Secondary Peaks... function analyzes all of your sequences for potential heterozygotes. It’s easy to control the stringency that defines a heterozygote.
19年来，公司始终秉承、专注、专心的发展理念，厚积薄发，积累了大量的人才、技术以及行业经验，在行业内得到了大量用户的认可和高度价。
http://turntech8843.b2b168.com
