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科学软件网是一个以引进国研软件,提供软件服务的营业网站,网站由北京天演融智软件有限公司创办,旨在为国内高校、科研院所和以研发为主的企业事业单位提供的科研软件及相关软件服务。截止目前,科学软件网已获得数百家国际软件公司正式授权,代理销售科研软件达一千余种,软件涵盖领域包括经管,仿真,地球地理,生物化学,工程科学,排版及网络管理等。同时,还提供培训、课程(包含34款软件,66门课程)、实验室解决方案和项目咨询等服务。
功能特征
物种试验
基因芯片的基因拼接/选择性剪接
外显子连接引物设计
实时PCR引物设计
TaqMan探针设计
SyBR绿色底漆设计
分子信标设计
FRET探针设计
微阵列探针设计
精密化验设计
数据库支持
输入输出格式
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What is Alternative Splicing?
The coding and non-coding fragments of the gene can be arranged in different ways. When this produces different m-RNA sequences from the same parent gene, the phenomenon is known as Alternative Splicing. The biological consequences of this process can be severe as the same gene leads to formation of different proteins which may be functional, non-functional or malfunctioning. The varied forms of the splicing events are known as splice variants. And as outlines above, AlleleID® could be used for splice variant detection using microarray experiments.
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Specifying Sequences: Specify the sequences you would like to detect in the mix by moving them to the "Bind To" box.
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AlleleID® Provides a Number of Options for Species Identification
Unique Probes with Unique Primers: When the probe type chosen is Unique, AlleleID® designs probes to identify each sequence in the Bind To box, one probe per sequence. The program searches for base positions that are unique to each individual sequence in the alignment. The probes are centered as close as possible over these unique bases, so that even when the mismatch is only one base, the assay succeeds.
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