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北京天演融智软件有限公司(科学软件网)前身是北京世纪天演科技有限公司,成立于2001年,专注为国内高校、科研院所和以研发为主的企事业单位提供科研软件和服务的国家。
Dual Labeled Probe Design
Beacon Designer™ currently supports four probe based chemistries:
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Automate Your Real Time PCR Primer and Probe Design
Beacon Designer™ automates the design of real time primers and probes. It is used by molecular biologists worldwide to design successful real time PCR assays. It saves the time and the money involved in failed experiments. Beacon Designer™ is a flexible solution to your real time primer and probe design needs and pays for itself many times over.
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The DNA sample is first treated with sodium bisulphite which converts the unmethylated cytosine bases to . The methylated cytosines on the other hand, remain unaffected. Methyl Specific primers are designed to anneal with bisulphite converted DNA. This sample is amplified by PCR replacing the with thymine. A TaqMan® probe is then used to detect the methylated strand.
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HRMA Assay Design
Beacon Designer™ offers a comprehensive solution for mutation detection. High Resolution Melting Analysis (HRMA) is a more cost-effective method than probe-based genotyping analysis. The program employs proprietary algorithms that enables designing the best primers for detecting mutations.
2020年,北京天演融智软件有限公司申请高等教育司产学合作协同育人项目,“大数据”和“机器学习”师资培训项目,以及基于OBE的教考分离改革与教学评测项目已获得批准。我们将会跟更多的高校合作,产学融合协同育人。
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