使用期限*
许可形式单机
原产地美国
介质下载
适用平台windows,mac
北京天演融智软件有限公司(科学软件网)前身是北京世纪天演科技有限公司,成立于2001年,专注为国内高校、科研院所和以研发为主的企事业单位提供科研软件和服务的国家。
Gene Codes is committed to bringing you a wide variety of alignment and assembly algorithms developed and published in peer-reviewed journals, but making them accessible to non-engineers. For example, GSNAP (Tom Wu, Genentech, Inc.) is recognized as one of the best algorithms for correctly identifying splice junctions. A bioinformatics specialist might invoke the program like this:
SANGER DNA ANALYSIS
Sequencher's extensive Sanger analysis features are the foundation it was built upon. Customizable from start to finish there is no other program that offers you as much power as Sequencher. With an easy to use interface that has been honed over 25 years, first time users will feel like a pro in minutes. Everything from trimming reads, custom assembly and alignment algorithms, variation tables, summary reports, annotation; the list goes on and on. Come see why Sequencher has been published in tens of thousands of research articles, and peer-reviewed journals. Power with Simplicity.
Sequencher DNA序列分析软件是科学家们*的工具。持续发展和改进**过25年,Sequencher提供了**的功能特征,成千上万的出版物都有相关的应用介绍。新手用户可以以少的时间投资产生结果,而有经验的用户会惊叹于功能的深度和控制。Sequencher自带各种专有算法,可以为Sanger, Next-Gen Sequencing (NGS)和RNA-Seq序列数据生成结果。
甲基化研究
几十年来,DNA甲基化被认为在基因表达中起着重要的作用。当用亚硫酸氢盐处理DNA时,除非胞嘧啶甲基化,任何胞嘧啶都被转换成尿嘧啶。GSNAP将从亚硫酸氢盐处理的DNA测序获得的下一代测序读数校准为参考序列,以不掩盖真正错配的方式排列它们,但当用亚硫酸氢盐处理未甲基化DNA时仍然暴露发生的C到T失配。
RNA耐受性比对
GSNAP已经更新,现在包含A-G容错对齐模式。使用这种模式的情况下,您的mRNA可能已被ADAR基因编辑,使腺苷转化为肌苷。当测序时,I被视为G。该版本还引入了用于新的RNA耐受模式和甲基化分析的滞留和非滞留模式。当您的实验室协议允许5’到3’基因组读取和它们在每个链上的反向互补时,使用非搁浅模式。
查看器
Tablet是下一代序列比对的高性能查看器。以许多不同的模式查看和审查您的Maq, GSNAP,
BWA-MEN或Velvet结果,用不同的颜色和阅读方向**显示。获取个别读数和读取成对的信息,以及排列读取的堆叠以显示配对。Tablet可以控制转换、缩放以及**变异基,以便让您的阅读变得*。
You can even use the Reference Sequence to guide the removal of sequences outside your region of interest or fill gaps in the sequence coverage.
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